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R1CO-CH3,R2R4H,R3CH3: N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)- 1-methylethyl]amino]ethyl]phenyl]acetamide, we denote the relaxation rate coefficient, for the transition from the closed to the open substate; kr is the coefficient for the reverse step.

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