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The methylene bisphosphonate derivatives etidronate (34), alendronate (35), and the alkyl-substituted derivative 36 (Scheme 23.

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Macromolecule degradation Nucleic acids Proteins Polysaccharides Lipids and fats Nucleotides Amino acids Sugars Fatty acids Deamination Glycolysis -oxidation Pyruvate Acetyl-CoA Krebs cycle NH3 H2O CO2 Cell building blocks Oxidative respiration Ultimate metabolic products FIGURE 9. 7±14. The lateral dose profile may have large dependence on beam gantry angle and should therefore be verified for each option, at prime gantry angles.

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Authors Acknowledgments We would like to thank all the staff at Wiley who have supported this project, from start to finish. Bullock and J.

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