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24c. 288 Index Facilitated diffusion, 39 Fascicles, 108 Fever, 229 Ficks first law, 38 Fiducial point, 150, 194 Filling phase, 130, 237 Firing rate, 100, 132 First diagnostic instrument, 14 First messenger, 51 First node of Ranvier, 90, 96, 103 Flow of ions, 63 Fluid resistance, 144 Forward flow, 162 Fourier analysis, 148 Fourier series, 148 complex amplitudes, 151 sinusoidal waves, 151 FrankStarling law, 126, 233 Free run of circadian clock, 267 Freezing, 228 Frequency coding, 99, 103 Frequency coupling, 231, 269 Frequency domain, 192, 260 Optiojs of incident and reflected waves, 168 Gated channels, 49, 53 acetylcholine-gated channels, 52, 53, 86 all-or-none fashion, 50, 52 Ca2C-activated Ca2C channels, 114 Ca2C-activated Ca2C release, 120 Ca2C-activated KC channel, 53 calcium release channels, 114 cross-sensitive channels, 88 directly gated channel, 51 G-protein-gated channels, 51 G-protein-gated KC channels, 84 indirect gating, 51 nonactivable state, 52 phosphorylation-gated channel, 52 refractory state, 52 stimulus-gated channels, 93 stretch-gated Ca2C channels, 119 stretch-gated channel, 52 transmitter-gated channels, 51, 83, 95 voltage-gated Ca2C channels, 51, 82, 88, 114, 120, 124 voltage-gated channels, 49, 95 voltage-gated channels for NaC and KC, 124 voltage-gated KC channels, 50, 53, 66, 101, 120, 124 voltage-gated NaC channels, 51, 53, 65, 80, 101, 120 Generalized transfer function, 168 Giant axons, 48, 80 metabolic efficiency, 48, 79 Glycine, 84 Glycoproteins, 33 GoldmanHodgkinKatz equation, 58 G-protein-gated channels, 51 G-protein-gated KC channels, 84 G-proteins, 94 Graded, 89 contractions, 118 opening, 52 potential, 52, 89 stimulus, 99 Hair bundle, 94 Heart, 121 atria, 121 atrioventricular node, 124, 127, 256 circulatory system, 133 conductive system, 123 contractility of heart, 133, 254 contraction force, 160, 233 excitation, 131 fibrous skeleton, 122 internodal fibers, 124 motion of myocardium, 242 pressurevolume relationship, 133 septum, 123 sinoatrial node, 123, 124, 126, 186, 256 valves, 122, 132 ventricles, 121 Heart rate, 18, 131, 132, 140, 187, 231, 236, 239, 266 instantaneous fC186 quotient of fC to fR, 238 respiratory modulation of fC237 sinoatrial node, 123, 124, 126, 186, 256 Heart rate turbulence, 258 Heart rate variability, 188, 262 autonomic nervous system, 120, 132, 186, 236 fiducial point, 194 high-frequency, 189 long-range correlations, 193 low-frequency, 189 physiological state, 188 ratio of the LFHF, 190 requirements for HRV analysis, 193 rhythmograms, 188 short-range correlations, 193 very-low-frequency, 191 Protein Engineering 203 culty with this method is the conformational entropy to be overcome as a result of the randomly fluctuating unfolded protein.

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