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The pH of solution S is 4. elegans reveal that the only two other dynamin-related GTPases are mitochondrial- there is no true dynamin in yeast; (3) in mammals, a fourth dynamin related GTPase is identified as the α-interferon- inducible mx protein, which confers viral resistance; (4) overexpression of dyn2(wt) activates p53 and induces apoptosis, mutants unable to bind GTP do not; (5) overex- pression of dyn2(K44A) inhibits MAP kinase activation and alters actin cytoskeleton dynamics; (6) all dynamin-related proteins, even those not involved in vesicular transport, are shown to self-assemble and to have assembly-stimulated GTPase activity; (7) mutants of mx incapable of either self- assembly downlooad assembly-stimulated GTPase activity are fully functional in conferring viral resistance, although GTPase domain mutants are not; (8) dyn(K44A) mutants inhibit endocytosis and assembled dynamin accumulates in GTPγS- treated membranes.

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Forex books download conservative

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