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3 The vector space structure on T,M In the heuristic, pictorial representation of tangent vectors to, for example, S" embedded in JRn', it is clear that (i) any two tangent vectors at a point p can be added to give a third; and (ii) a real multiple of a tangent vector is itself a tangent vector. 8 to 4. Cocaine-Induced Cardiovascular Toxicity: Overview The cardiovascular complications of cocaine are ascribed to its inhibition of norepinephrine reuptake and stimulation of central sympathetic outflow, raising circulating catechol- amines up to fivefold (35).

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