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The peptide binds to the major histocompatibility complex (MHC) molecule pouch through its anchor residues, enabling the interaction between the T cell receptors (TCR) binding residues, l-i)y) are zero, the energies of g±i)y are not changed to first order infeuA',while their wave functions become kv«]A', kv lsiy lgiy o(A ' - A ') 11 I Sincewehavechosenareddetuning(50)A,is negative It;follows from E1- 3-2°)that l-iis more populated than ISl)z'- u 0 S 0 - » n n (3 21) ' - l i- ) W e show in the next subsection how this motion-induced population difference can give rise to a new much moTe efficient friction mechanism than th e one used in Doppler cooling.

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