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The following pathological variables have been shown to correlate with variations in the radiological appearance of DCIS: Architectural pattern Cell size Necrosis C-erbB-2 expression p53 expression and MIB1 Oestrogen receptor and progesterone receptor expression Architectural pattern The traditional classification of DCIS was based solely on architectural pattern; Holland and co-workers were the first to describe variations in the radiological appearances of DCIS according to architec- tural pattern9.

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