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(2006). It is well established that selected growth factors, proto-oncogenes and some chemicals play pivotal roles in normal human intrauterine ontogenesis and are also quite important in embryonal organogenesis, as well as neoplastic transformation (329).

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Black, An Introduction opfion Orthopedic Materials (Charles C Thomas, Springfield, IL, USA, 1975) 89. Acknowledgments We gratefully acknowledge financial support from ACI-IMPB045 from the Ministere de la Recherche et de la Technologie and from GDR 2417 du CNRS.

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